Serious Use Alternative 1 quinidine and pitolisant both increase QTc interval doxycycline yeast infection Treatment of Ovx ApoE mice with XYS significantly decreased HFD induced increases in hepatic steatosis and triglyceride TG content, accompanied by inhibition of liver X receptor О± LXRО±, sterol regulatory element binding protein SREBP 1c and its target lipogenic genes transcription